DEAFinal Rule

Schedules of Controlled Substances: Placement of N-Pyrrolidino Metonitazene and N-Pyrrolidino Protonitazene in Schedule I

HealthcareOther

Summary

The Drug Enforcement Administration (DEA) has added two synthetic drugs called N-Pyrrolidino Metonitazene and N-Pyrrolidino Protonitazene to the list of Schedule I controlled substances, meaning they are now illegal to make, sell, or possess without a special license. These are powerful opioid-like drugs that have been linked to overdoses and deaths, and this ban aims to protect public health by preventing their distribution.

Key Points

  • 1Two synthetic drugs (N-Pyrrolidino Metonitazene and N-Pyrrolidino Protonitazene) are now classified as Schedule I controlled substances, making them illegal to produce, distribute, or possess
  • 2This classification means these drugs are considered to have high potential for abuse and no currently accepted medical use in the United States
  • 3People caught manufacturing, selling, or possessing these drugs face serious federal criminal penalties, including prison time and fines
  • 4The ban addresses an emerging public health threat, as these drugs have been increasingly found in drug supplies and linked to overdose deaths
  • 5This regulation took effect on January 12, 2026, and law enforcement agencies can now actively prosecute violations

Key Dates

Published

January 12, 2026

This summary is for informational purposes only. It may not capture all nuances of the regulation. Always refer to the official text for authoritative information.

The Digest Network